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Local delivery of insulin/IGF-1 for bone regeneration: carriers, strategies, and effects

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Colin IM, Grard KM

The main concerns include additive gastrointestinal effects (nausea, vomiting, diarrhoea), cognitive side effects from topiramate (difficulty concentrating, memory problems), and potential for excessive weight loss

The jury is still out on the long-term effects and results of GLP-1s, but early signs indicate stabilization for diabetic members with respect to cost and clinical outcomes

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